Rejection of transplant

No lives could be saved by any of these gifts until the scientific community examined the mysteries of rejection. Since the discovery of blood groups scientists have continued to make monumental strides in the understanding of the human immune system.

Transplant rejection has come to be recognized as the body’s attempt to repel foreign tissue, much the same way it would attack an unwelcome virus or bacteria. But since an organ is not an unwanted invader, steps are taken to insure compatibility.

Before organ donation proceeds, potential organ donors are rigorously screened on a case by case basis to ensure that risks of infection, disease, complications or donated organs being in a sub-optimal state are minimized or eliminated.

Hyper acute rejection, usually the result of mismatched blood type, will occur within minutes of the surgery and the only solution is the removal of the organ.

Acute rejection often occurs within one week to three months of the surgery, and is usually treated with a short course of strong corticosteroids that suppress the immune system.

Chronic rejection is a longterm failure of the organ, it is irreversible and cannot be treated effectively. So this is one of the most dangerous one.. Patient can die all at once. doctors should be carful while approving.

A bone marrow transplant can also decrease rejection, but only if the marrow comes from the same donor as the transplanted organ.